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Federer also lost his first match in the event last year, to Fernando Gonzalez, but came back to clinch his second consecutive title.
In Davis Cup news last night it was revealed Nadal is unlikely to be fit for Spain's final against Argentina in Mar del Plata on November 21-23.
His coach, and uncle, Tony Nadal, said Nadal had very little chance of participating in the final because of tendinitis in his right knee.
His absence would be a boost to Argentina in its hopes of winning the cup for the first time.
Earlier in Shanghai, Novak Djokovic had launched a charm offensive designed to soften his abrasive image after alienating several of his peers with injury time-outs.
Troubled by a vicious response from US Open crowds after a spat with Andy Roddick over the number of times he has on-court treatment, Djokovic tried to hose down the issue.
The Serb was jeered in New York after berating Roddick, who accused the Australian Open champion of suffering 16 different injuries
The seventh season of Scrubs seems to be missing just a little bit of its timing and charm, only just a little though. I completely understand why. This is the strike-shortened season, so there s only 11 episodes in this set. The writers strike threw a lot of shows off, and you can see how it affected Scurbs.
The final episode in the season seems more like an episode that would be aired in the middle of the season to break up the formula a little bit, much like the musical did in the sixth season
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